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Differential response to acute low dose radiation in primary and immortalized endothelial cells

21 May 2013

Abstract excerpt

PURPOSE: The low dose radiation response of primary human umbilical vein endothelial cells (HUVEC) and its immortalized derivative, the EA.hy926 cell line, was evaluated and compared. MATERIAL AND METHODS: DNA damage and repair, cell cycle progression, apoptosis and cellular morphology in HUVEC and EA.hy926 were evaluated after exposure to low (0.05-0.5 Gy) and high doses (2 and 5 Gy) of acute X-rays. RESULTS:...

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PMID: 23692394
DOI: 10.3109/09553002.2013.806831

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