Article
Determination of optimal cutoff value to accurately identify glucose-6-phosphate dehydrogenase-deficient heterozygous female neonates.
Clinica chimica acta; international journal of clinical chemistry - 23 Sept 2013
Miao Jing-Kun, Chen Qi-Xiong, Bao Li-Ming, Huang Yi, Zhang Juan, Wan Ke-Xing, Yi Jing, Wang Shi-Yi, Zou Lin, Li Ting-Yu
Abstract excerpt
BACKGROUND: Conventional screening tests to assess G6PD deficiency use a low cutoff value of 2.10 U/gHb which may not be adequate for detecting females with heterozygous deficiency. The aim of present study was to determine an appropriate cutoff value with increased sensitivity in identifying G6PD-deficient heterozygous females. METHODS: G6PD activity analysis was performed on 51,747 neonates using...
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