Article
Genetic diversity of HA1 domain of heammaglutinin gene of influenza A(H1N1)pdm09 in Tunisia.
Virology journal - 16 May 2013
El Moussi Awatef, Ben Hadj Kacem Mohamed Ali, Pozo Francisco, Ledesma Juan, Cuevas Maria Teresa, Casas Inmaculada, Slim Amine
Abstract excerpt
We present major results concerning isolation and determination of the nucleotide sequence of hemagglutinin (HA1) of the pandemic (H1N1)pdm09 influenza viruses found in Tunisia. Amino acid analysis revealed minor amino acid changes in the antigenic or receptor-binding domains. We found mutations that were also present in 1918 pandemic virus, which includes S183P in 4 and S185T mutation in 19 of 27 viruses...
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