Article
Progress in molecular-based management of differentiated thyroid cancer.
Lancet (London, England) - 23 Mar 2013
Xing Mingzhao, Haugen Bryan R, Schlumberger Martin
Abstract excerpt
Substantial developments have occurred in the past 5-10 years in clinical translational research of thyroid cancer. Diagnostic molecular markers, such as RET-PTC, RAS, and BRAF(V600E) mutations; galectin 3; and a new gene expression classifier, are outstanding examples that have improved diagnosis of thyroid nodules. BRAF mutation is a prognostic genetic marker that has improved risk stratification and hence...
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