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Article

Evidence for transgenerational metabolic programming in Drosophila.

Disease models & mechanisms - 1 Sept 2013

Buescher Jessica L, Musselman Laura P, Wilson Christina A, Lang Tieming, Keleher Madeline, Baranski Thomas J, Duncan Jennifer G

Abstract excerpt

Worldwide epidemiologic studies have repeatedly demonstrated an association between prenatal nutritional environment, birth weight and susceptibility to adult diseases including obesity, cardiovascular disease and type 2 diabetes. Despite advances in mammalian model systems, the molecular mechanisms underlying this phenomenon are unclear, but might involve programming mechanisms such as epigenetics. Here we...

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Identifiers

PMID: 23649823
DOI: 10.1242/dmm.011924
PMCID: PMC3759332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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