Article
Systematic analysis of experimental phenotype data reveals gene functions.
PloS one - 1 Jan 2013
Hoehndorf Robert, Hardy Nigel W, Osumi-Sutherland David, Tweedie Susan, Schofield Paul N, Gkoutos Georgios V
Abstract excerpt
High-throughput phenotyping projects in model organisms have the potential to improve our understanding of gene functions and their role in living organisms. We have developed a computational, knowledge-based approach to automatically infer gene functions from phenotypic manifestations and applie...
Topics
- Animals
- Caenorhabditis elegans
- Computational Biology
- Drosophila melanogaster
- Humans
- Mice
- Molecular Sequence Annotation
- Phenotype
- Saccharomyces cerevisiae
- Zebrafish