Article
Systematic analysis of experimental phenotype data reveals gene functions.
PloS one - 1 Jan 2013
Hoehndorf Robert, Hardy Nigel W, Osumi-Sutherland David, Tweedie Susan, Schofield Paul N, Gkoutos Georgios V
Abstract excerpt
High-throughput phenotyping projects in model organisms have the potential to improve our understanding of gene functions and their role in living organisms. We have developed a computational, knowledge-based approach to automatically infer gene functions from phenotypic manifestations and applied this approach to yeast (Saccharomyces cerevisiae), nematode worm (Caenorhabditis elegans), zebrafish (Danio rerio),...
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