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Article

Medical management of endometriosis: emerging evidence linking inflammation to disease pathophysiology.

Minerva ginecologica - 1 Apr 2013

Bruner-Tran K L, Herington J L, Duleba A J, Taylor H S, Osteen K G

Abstract excerpt

Progesterone action normally mediates the balance between anti-inflammatory and proinflammatory processes throughout the female reproductive tract. However, in women with endometriosis, endometrial progesterone resistance, characterized by alterations in progesterone responsive gene and protein expression, is now considered a central element in disease pathophysiology. Recent studies additionally suggest that the...

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PMID: 23598784
PMCID: PMC3718308

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