Article
Analysis of a gene co-expression network establishes robust association between Col5a2 and ischemic heart disease.
BMC medical genomics - 10 Apr 2013
Azuaje Francisco, Zhang Lu, Jeanty Céline, Puhl Sarah-Lena, Rodius Sophie, Wagner Daniel R
Abstract excerpt
BACKGROUND: This study aims to expand knowledge of the complex process of myocardial infarction (MI) through the application of a systems-based approach. METHODS: We generated a gene co-expression network from microarray data originating from a mouse model of MI. We characterized it on the basis of connectivity patterns and independent biological information. The potential clinical novelty and relevance of top...
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