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Article

Genetic variation in HIF signaling underlies quantitative variation in physiological and life-history traits within lowland butterfly populations.

Evolution; international journal of organic evolution - 1 Apr 2013

Marden James H, Fescemyer Howard W, Schilder Rudolf J, Doerfler William R, Vera Juan C, Wheat Christopher W

Abstract excerpt

Oxygen conductance to the tissues determines aerobic metabolic performance in most eukaryotes but has cost/benefit tradeoffs. Here we examine in lowland populations of a butterfly a genetic polymorphism affecting oxygen conductance via the hypoxia-inducible factor (HIF) pathway, which senses intracellular oxygen and controls the development of oxygen delivery networks. Genetically distinct clades of Glanville...

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PMID: 23550759
DOI: 10.1111/evo.12004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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