Article
Advanced BMP Gene Therapies for Temporal and Spatial Control of Bone Regeneration
28 Mar 2013
Abstract excerpt
Spatial and temporal patterns of bone morphogenetic protein (BMP) signaling are crucial to the assembly of appropriately positioned and shaped bones of the face and head. This review advances the hypothesis that reconstitution of such patterns with cutting-edge gene therapies will transform the clinical management of craniofacial bone defects attributed to trauma, disease, or surgical resection. Gradients in BMP...
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