Article
Association KRAS G13D tumor mutated outcome in patients with chemotherapy refractory metastatic colorectal cancer treated with cetuximab.
Hepato-gastroenterology - 1 Jan 2000
Tural Deniz, Selcukbiricik Fatih, Erdamar Sibel, Ozkurt Canan Unlu, Yanmaz Teoman, Mandel Nil Molinas, Serdengeçti Süheyla
Abstract excerpt
BACKGROUND/AIMS: Cetuximab is currently approved for the treatment of metastatic colorectal cancer (mCR) with KRAS wild-type. Prior few studies demonstrated that G13D mutated tumors could benefit from cetuximab. This study aims to investigate whether KRAS G13D mutated tumors benefit from cetuximab in the chemotherapy refractory patients. METHODOLOGY: We retrospectively compared progression-free survival (PFS),...
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