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The actin-based machinery ofTrichomonas vaginalismediates flagellate-amoeboid transition and migration across host tissue

26 Mar 2013

Abstract excerpt

Trichomonas vaginalis is the most widespread non-viral pathogen of the human urogenital tract, infecting ∼ 3% of the world's population annually. At the onset of infection the protist changes morphology within minutes: the flagellated free-swimming cell converts into the amoeboid-adherent stage. The molecular machinery of this process is not well studied, but is thought to involve actin reorganization. We have...

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PMID: 23530917
DOI: 10.1111/cmi.12144

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