Article
Molecular analysis of factor XII gene in Thai patients with factor XII deficiency.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2013
Singhamatr Pon, Kanjanapongkul Somjai, Rojnuckarin Ponlapat
Abstract excerpt
Factor XII is the initiating protein of the intrinsic coagulation pathway. It activates factor X after being activated by the so called 'contact system'. Both congenital factor XII deficiency, usually without bleeding symptoms, and several factor XII polymorphisms with possible thrombotic tendency have been described. In the presented work, two Thai patients with congenital factor XII deficiency have been studied...
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