Article
Safety aspects of protease inhibitors for chronic hepatitis C: adverse events and drug-to-drug interactions.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Teixeira Rosângela, Nascimento Yone de Almeida, Crespo Déborah
Abstract excerpt
The standard of care therapy of chronic hepatitis C with the combination of pegylated interferon and ribavirin for 24 or 48 weeks was a remarkable accomplishment of the past decade. However, sustained virological responses rates of about 80% (genotypes 2-3) and 50% (genotype 1) were not satisfactory especially for patients infected with genotype 1. Important advances in the biology of HCV have made possible the...
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