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Article

Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms.

Antimicrobial agents and chemotherapy - 1 May 2013

Chiang Wen-Chi, Nilsson Martin, Jensen Peter Østrup, Høiby Niels, Nielsen Thomas E, Givskov Michael, Tolker-Nielsen Tim

Abstract excerpt

Within recent years, it has been established that extracellular DNA is a key constituent of the matrix of microbial biofilms. In addition, it has recently been demonstrated that DNA binds positively charged antimicrobials such as aminoglycosides and antimicrobial peptides. In the present study, w...

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Identifiers

PMID: 23478967
DOI: 10.1128/AAC.00001-13
PMCID: PMC3632962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23478967-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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