Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Chemical Proteomics Approach to Profiling the ATP-binding Proteome of Mycobacterium tuberculosis

5 Mar 2013

Abstract excerpt

Tuberculosis, caused by Mycobacterium tuberculosis, remains one of the leading causes of death worldwide despite extensive research, directly observed therapy using multidrug regimens, and the widespread use of a vaccine. The majority of patients harbor the bacterium in a state of metabolic dormancy. New drugs with novel modes of action are needed to target essential metabolic pathways in M. tuberculosis;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Synthase and ATPases Research
Share to Biochemical and Molecular Research
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23462205
DOI: 10.1074/mcp.m112.025635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Chemical Proteomics Approach to Profiling the ATP-binding Proteome of Mycobacterium tuberculosisPMID 23462205Read ↗

Target Identification in Anti-Tuberculosis Drug DiscoverySemantic proximity Read ↗

Deciphering the Proteomic Landscape of Mycobacterium tuberculosis in Response to Acid and Oxidative StressesSemantic proximity Read ↗

Mycobacterium tuberculosis Proteome Response to Antituberculosis Compounds Reveals Metabolic “Escape” Pathways That Prolong Bacterial SurvivalSemantic proximity Read ↗

Modeling Phenotypic Metabolic Adaptations of Mycobacterium tuberculosis H37Rv under HypoxiaSemantic proximity Read ↗

Targeting the Proteostasis Network for Mycobacterial Drug DiscoverySemantic proximity Read ↗

The role of thioredoxin proteins in <i>Mycobacterium tuberculosis</i> probed by proteome-wide target profilingSemantic proximity Read ↗

Metabolic switching and cell wall remodelling of <i>Mycobacterium tuberculosis</i> during bone tuberculosisSemantic proximity Read ↗

Comparative transcriptomics reveals PrrAB-mediated control of metabolic, respiration, energy-generating, and dormancy pathways in Mycobacterium smegmatis.Semantic proximity Read ↗

Mycobacterium tuberculosis MetabolismSemantic proximity Read ↗

Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discoverySemantic proximity Read ↗

Evolution of Mycolic Acid Biosynthesis Genes and Their Regulation during Starvation in Mycobacterium tuberculosisSemantic proximity Read ↗

Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.