Article
Transforming growth factor beta 1 is a novel susceptibility gene for adolescent idiopathic scoliosis.
Spine - 20 May 2013
Ryzhkov Igor I, Borzilov Eugeny E, Churnosov Mikhail I, Ataman Alexander V, Dedkov Andrey A, Polonikov Alexey V
Abstract excerpt
STUDY DESIGN: A genetic association study of the transforming growth factor beta 1 (TGFB1) gene with adolescent idiopathic scoliosis (AIS) in Russian population. OBJECTIVE: To determine whether common genetic polymorphisms C-509T (rs1800469) and Arg25Pro (rs1800471) of the TGFB1 gene are associated with susceptibility to AIS. SUMMARY OF BACKGROUND DATA: An importance of growth factors for the pathogenesis of AIS...
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