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A Review on JC Virus Infection in Kidney Transplant Recipients

1 Jan 2013

Abstract excerpt

The polyomavirus (PyV), JC virus (JCV), is a small nonenveloped DNA virus that asymptomatically infects about 80% of healthy adults and establishes latency in the kidney tissue. In case of immunodeficient hosts, JCV can lytically infect the oligodendrocytes, causing a fatal demyelinating disease, known as progressive multifocal leukoencephalopathy (PML). Although the reactivation of another human PyV, BK virus...

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PMID: 23424601
DOI: 10.1155/2013/926391

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