Article
Long telomeres in peripheral blood leukocytes are associated with an increased risk of soft tissue sarcoma
13 Feb 2013
Abstract excerpt
BACKGROUND: Human telomeres consisting of long, tandem repeats of the nucleotide sequence TTAGGG at the chromosome ends are essential for maintaining chromosomal stability. Previous epidemiologic studies have indicated that shorter telomere length in peripheral blood leukocytes (PBLs) is associated with the development of many cancers. However, the relation between PBL telomere length and the risk of soft tissue...
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