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Article

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.

Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2013

van Kasteren Puck B, Bailey-Elkin Ben A, James Terrence W, Ninaber Dennis K, Beugeling Corrine, Khajehpour Mazdak, Snijder Eric J, Mark Brian L, Kikkert Marjolein

Abstract excerpt

Protein ubiquitination regulates important innate immune responses. The discovery of viruses encoding deubiquitinating enzymes (DUBs) suggests they remove ubiquitin to evade ubiquitin-dependent antiviral responses; however, this has never been conclusively demonstrated in virus-infected cells. Ar...

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Identifiers

PMID: 23401522
DOI: 10.1073/pnas.1218464110
PMCID: PMC3587229

Genes

PLP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23401522-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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