Fangchinoline Induces G1 Arrest in Breast Cancer Cells Through Cell‐Cycle Regulation

Abstract excerpt

Fangchinoline, an alkaloid derived from the dry roots of Stephaniae tetrandrine S. Moore (Menispermaceae), has been shown to possess cytotoxic, anti-inflammatory, and antioxidant properties. In this study, we used Fangchinoline to inhibit breast cancer cell proliferation and to investigate its underlying molecular mechanisms. Human breast cancer cell lines, MCF-7 and MDA-MB-231, were both used in this study. We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Berberine and alkaloids research
• Share to Bioactive natural compounds
• Share to Cancer-related Molecular Pathways