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Article

Phenotypic changes associated with RNA interference silencing of chalcone synthase in apple (Malus × domestica).

The Plant journal : for cell and molecular biology - 1 May 2013

Dare Andrew P, Tomes Sumathi, Jones Midori, McGhie Tony K, Stevenson David E, Johnson Ross A, Greenwood David R, Hellens Roger P

Abstract excerpt

We have identified in apple (Malus × domestica) three chalcone synthase (CHS) genes. In order to understand the functional redundancy of this gene family RNA interference knockout lines were generated where all three of these genes were down-regulated. These lines had no detectable anthocyanins and radically reduced concentrations of dihydrochalcones and flavonoids. Surprisingly, down-regulation of CHS also led...

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PMID: 23398045
DOI: 10.1111/tpj.12140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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