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Article

Evolution of equine influenza virus in vaccinated horses.

Journal of virology - 1 Apr 2013

Murcia Pablo R, Baillie Gregory J, Stack J Conrad, Jervis Carley, Elton Debra, Mumford Jennifer A, Daly Janet, Kellam Paul, Grenfell Bryan T, Holmes Edward C, Wood James L N

Abstract excerpt

Influenza A viruses are characterized by their ability to evade host immunity, even in vaccinated individuals. To determine how prior immunity shapes viral diversity in vivo, we studied the intra- and interhost evolution of equine influenza virus in vaccinated horses. Although the level and structure of genetic diversity were similar to those in naïve horses, intrahost bottlenecks may be more stringent in...

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Source

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Identifiers

PMID: 23388708
DOI: 10.1128/JVI.03379-12
PMCID: PMC3624384

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Source receipt: pubmed, retrieved 7 Sept 2026.

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