Article
M-pick, a modularity-based method for OTU picking of 16S rRNA sequences.
BMC bioinformatics - 7 Feb 2013
Wang Xiaoyu, Yao Jin, Sun Yijun, Mai Volker
Abstract excerpt
BACKGROUND: Binning 16S rRNA sequences into operational taxonomic units (OTUs) is an initial crucial step in analyzing large sequence datasets generated to determine microbial community compositions in various environments including that of the human gut. Various methods have been developed, but most suffer from either inaccuracies or from being unable to handle millions of sequences generated in current studies....
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