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Article

Analysis of CAG repeats in five SCA loci in Mexican population: epidemiological evidence of a SCA7 founder effect.

Clinical genetics - 1 Feb 2014

Magaña J J, Tapia-Guerrero Y S, Velázquez-Pérez L, Cerecedo-Zapata C M, Maldonado-Rodríguez M, Jano-Ito J S, Leyva-García N, González-Piña R, Martínez-Cruz E, Hernández-Hernández O, Cisneros B

Abstract excerpt

Spinocerebellar ataxias (SCA) are a heterogeneous group of neurodegenerative disorders. CAG (cytosine-adenine-guanine) trinucleotide repeat expansions in the causative genes have been identified as the cause of different SCA. In this study, we simultaneously genotyped SCA1, SCA2, SCA3, SCA6, and SCA7 applying a fluorescent multiplex polymerase chain reaction assay. We analyzed 10 families with SCA (64 patients)...

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PMID: 23368522
DOI: 10.1111/cge.12114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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