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Microbiotas from UC patients display altered metabolism and reduced ability of LAB to colonize mucus

23 Jan 2013

Abstract excerpt

We compared fecal microbial communities derived either from Ulcerative Colitis (UC) patients in remission (n = 4) or in relapse (n = 4), or from healthy subjects (n = 4). These communities were used for inoculation of a dynamic in vitro gut model, which contained integrated mucin-covered microcosms. We found that the microbiota of the 'mucus' largely differed from that of the 'lumen'. This was partly due to...

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PMID: 23346367
DOI: 10.1038/srep01110

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