[Early and late effects of the cytogenetic action of doxorubicin].

Article

[Early and late effects of the cytogenetic action of doxorubicin].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 1990

Klimova M Iu, Novitskiĭ V V, Gol'dberg E D

Abstract excerpt

Cytogenetic disorders in hemopoietic cells of the bone marrow were studied on mice CBA at early and late periods after exposure to MIDs of doxorubicin, an anthracycline antibiotic. It was shown that at the early period doxorubicin induced aberrations, mainly of the chromatid type, in the hemopoie...

Topics

Animals
Bone Marrow
Chromosome Aberrations
Doxorubicin
Erythrocytes
Hematopoietic Stem Cells
Mice
Mice, Inbred CBA
Micronucleus Tests
Mutation
Time Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.