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Article

Social investigation and long-term recognition memory performance in 129S1/SvImJ and C57BL/6JOlaHsd mice and their hybrids.

PloS one - 1 Jan 2013

Hädicke Jana, Engelmann Mario

Abstract excerpt

When tested for their behavioural performance, the mixed genetic background of transgenic mice is a critical, but often ignored, issue. Such issues can arise because of the significant differences in defined behavioural parameters between embryonic stem cell donor and recipient strains. In this context, the commonly used stem cell donor strain '129' shows 'deficits' in different paradigms for learning and...

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PMID: 23342157
DOI: 10.1371/journal.pone.0054427
PMCID: PMC3546984

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