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Article

Nonsynonymous polymorphisms in FAT4 gene are associated with the risk of esophageal cancer in an Eastern Chinese population.

International journal of cancer - 15 Jul 2013

Du Jiangbo, Ji Jian, Gao Yong, Xu Lin, Xu Jing, Zhu Chen, Gu Haiyong, Jiang Jie, Li Huizhang, Ma Hongxia, Hu Zhibin, Jin Guangfu, Guo Wei, Chen Xiaofei, Shen Hongbing

Abstract excerpt

FAT4 plays a crucial role in carcinogenesis as a key component of the Hippo signaling pathway. We hypothesized that potential functional polymorphisms in the FAT4 gene may modify the risk of esophageal cancer. To test this hypothesis, we evaluated the association between four nonsynonymous polymorphisms (rs1039808, rs12508222, rs1567047 and rs1014867) in FAT4 and esophageal cancer risk in a case-control study of...

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Identifiers

PMID: 23319386
DOI: 10.1002/ijc.28033

Genes

FAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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