Article
Kinetics and prediction of HBsAg loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2013
Boglione Lucio, D'Avolio Antonio, Cariti Giuseppe, Gregori Gabriella, Burdino Elisa, Baietto Lorena, Cusato Jessica, Ghisetti Valeria, De Rosa Francesco G, Di Perri Giovanni
Abstract excerpt
BACKGROUND & AIMS: In patients affected by chronic hepatitis because of HBV infection, long-term suppressive therapy with nucleos(t)ides analogues in the HBeAg- patients has shown low effects on HBsAg titre (qHBsAg) decrease, and HBsAg loss is difficult to achieve. Thus, in this type of patients the main goals of antiviral therapy is the suppression of HBV-DNA and ALT normalization. METHODS: We retrospectively...
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