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The intracellular progesterone receptor regulates CD4+ T cells and T cell-dependent antibody responses

10 Jan 2013

Abstract excerpt

Pg has distinct immunomodulatory properties involved in poorly understood immune phenomena, including maternal tolerance of the fetus, increased risk of certain infections during pregnancy or after Pg birth control, and pregnancy-associated remission of autoimmune disease. Several potential mechanisms have been identified, including alteration of Th1 and Treg activity, but the precise cellular and molecular...

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PMID: 23307939
DOI: 10.1189/jlb.1012491

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