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Article

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

10 Jan 2013

Abstract excerpt

Metabolism and immunity are inextricably linked both to each other and to organism-wide function, allowing mammals to adapt to changes in their internal and external environments. In the modern context of obesogenic diets and lifestyles, however, these adaptive responses can have deleterious consequences. In this Review, we discuss the pleiotropic actions of inflammation and insulin resistance in metabolic...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 23307735
DOI: 10.1126/science.1230721

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