Article
Second-line cetuximab/irinotecan versus oxaliplatin/fluoropyrimidines for metastatic colorectal cancer with wild-type KRAS.
Cancer science - 1 Apr 2013
Hong Yong Sang, Kim Hwa Jung, Park Seong Joon, Kim Kyu-Pyo, Lee Jae-Lyun, Park Jin Hong, Kim Jong Hoon, Lim Seok-Byung, Yu Chang Sik, Kim Jin Cheon, Baek Ji Yeon, Kim Sun Young, Kim Tae Won
Abstract excerpt
The goal of the present study was to compare the efficacy of the combination of cetuximab and irinotecan to the combination of oxaliplatin and fluoropyrimidines as second-line chemotherapy in patients with irinotecan-refractory and oxaliplatin-naïve metastatic colorectal cancer (mCRC) harboring wild-type KRAS. The study included 120 patients with mCRC who had progressed after irinotecan-containing first-line...
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