Article
Coiled-coil protein Scy is a key component of a multiprotein assembly controlling polarized growth in Streptomyces.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2013
Holmes Neil A, Walshaw John, Leggett Richard M, Thibessard Annabelle, Dalton Kate A, Gillespie Michael D, Hemmings Andrew M, Gust Bertolt, Kelemen Gabriella H
Abstract excerpt
Polarized growth in eukaryotes requires polar multiprotein complexes. Here, we establish that selection and maintenance of cell polarity for growth also requires a dedicated multiprotein assembly in the filamentous bacterium, Streptomyces coelicolor. We present evidence for a tip organizing center and confirm two of its main components: Scy (Streptomyces cytoskeletal element), a unique bacterial coiled-coil...
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