Article
The propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor.
Scientific reports - 17 Feb 2017
Yang Wen, Willemse Joost, Sawyer Elizabeth B, Lou Fei, Gong Weibin, Zhang Hong, Gras Sally L, Claessen Dennis, Perrett Sarah
Abstract excerpt
Streptomyces bacteria form reproductive aerial hyphae that are covered with a pattern of pairwise aligned fibrils called rodlets. The presence of the rodlet layer requires two homologous rodlin proteins, RdlA and RdlB, and the functional amyloid chaplin proteins, ChpA-H. In contrast to the redundancy shared among the eight chaplins, both RdlA and RdlB are indispensable for the establishment of this rodlet...
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