Article
Discordance in drug resistance-associated mutation patterns in marker genes of Plasmodium falciparum and Plasmodium knowlesi during coinfections.
The Journal of antimicrobial chemotherapy - 1 May 2013
Tyagi Rupesh K, Das Manoj K, Singh Shiv S, Sharma Yagya D
Abstract excerpt
OBJECTIVES: Human Plasmodium knowlesi infections have been reported from several South-East Asian countries, excluding India, but its drug susceptibility profile in mixed-infection cases remains unknown. METHODS: The chloroquine resistance transporter (CRT) and dihydrofolate reductase (DHFR) genes of P. knowlesi and other Plasmodium species were sequenced from clinical isolates obtained from malaria patients...
Topics
- Coinfection
- DNA, Protozoan
- Drug Resistance
- Genetic Variation
- Humans
- India
- Malaria
- Molecular Sequence Data
- Mutation, Missense
- Plasmodium
- Protozoan Proteins