Article
Disruption of the expression of a non-coding RNA significantly impairs cellular differentiation in Toxoplasma gondii.
International journal of molecular sciences - 28 Dec 2012
Patil Veerupaxagouda, Lescault Pamela J, Lirussi Dario, Thompson Ann B, Matrajt Mariana
Abstract excerpt
The protozoan parasite Toxoplasma gondii is an important human and veterinary pathogen. Asexual replication of T. gondii in humans and intermediate hosts is characterized by two forms: rapidly growing "tachyzoites" and latent "bradyzoite" tissue cysts. Tachyzoites are responsible for acute illness and congenital neurological birth defects, while the more slowly dividing bradyzoite form can remain latent within...
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