Article
Screening of mutant strain Streptomyces mediolani sp. AC37 for (-)-8-O-methyltetrangomycin production enhancement.
Journal of microbiology (Seoul, Korea) - 1 Dec 2012
Jiménez Jakeline Trejos, Sturdíková Maria, Brezová Vlasta, Svajdlenka Emil, Novotová Marta
Abstract excerpt
Streptomyces mediolani sp. AC37 was isolated from the root system of higher plant Taxus baccata and produced metabolite identified as (-)-8-O-methyltetrangomycin according to LC/MS/MS analysis. In our screening program for improvements of bioactive secondary metabolites from plant associate streptomycetes, mutation was used as a tool for the induction of genetic variations for selection of higher...
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