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Article

Haplotype analysis and ancient origin of the BRCA1 c.4035delA Baltic founder mutation.

European journal of medical genetics - 1 Mar 2013

Janavičius Ramūnas, Rudaitis Vilius, Feng Bing-Jian, Ozolina Silvija, Griškevičius Laimonas, Goldgar David, Tihomirova Laima

Abstract excerpt

Uncertainty exists about the origin of BRCA1 c.4035delA mutation which is prevalent in Baltic countries, with the highest frequency being in Lithuania (53% of all BRCA1 mutations), although formal founder mutation analysis by haplotype has not yet been undertaken. In this study we genotyped 78 un...

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Identifiers

PMID: 23274591
DOI: 10.1016/j.ejmg.2012.12.007

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23274591-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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