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Article

Molecular analysis of four cases of chronic granulomatous disease caused by defects in NCF-2: the gene encoding the p67-phox.

Iranian journal of allergy, asthma, and immunology - 1 Dec 2012

Badalzadeh Mohsen, Fattahi Fatemeh, Fazlollahi Mohammad Reza, Tajik Shaghayegh, Bemanian Mohammad Hassan, Behmanesh Fatemeh, Movahedi Massoud, Houshmand Massoud, Pourpak Zahra

Abstract excerpt

Chronic granulomatous disease (CGD), a rare inherited primary immunodeficiency disorder, is caused by mutation in any one of the genes encoding components of nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase enzyme. NCF2 gene (encoding P67-phox component) is one of them and its mutation is less common to cause CGD (around 5-6%). Here, we assessed mutation analysis of NCF2 in 4 CGD patients with p67-phox...

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Identifiers

PMID: 23264412
DOI: 011.04/ijaai.340344

Genes

NCF2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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