Article
Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome.
American journal of medical genetics. Part A - 1 Jan 2013
Mills Kimberly I, Anderson Jacqueline, Levy Philip T, Cole F Sessions, Silva Jennifer N A, Kulkarni Shashikant, Shinawi Marwan
Abstract excerpt
Wolff-Parkinson-White (WPW) syndrome is caused by preexcitation of the ventricular myocardium via an accessory pathway which increases the risk for paroxysmal supraventricular tachycardia. The condition is often sporadic and of unknown etiology in the majority of cases. Autosomal dominant inheritance and association with congenital heart defects or ventricular hypertrophy were described. Microdeletions of 20p12.3...
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