Article
[DNA sequence analysis of Jk(a-b-) phenotype of blood donors from Chengdu].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2012
Hong Ying, Gong Tian-xiang, Zhou Chang-hua
Abstract excerpt
OBJECTIVE: To study the molecular genetics characteristics of Jk(a-b-) phenotype of blood donors from Chengdu. METHODS: Exons 4-11 of the JK genes and their flanking intronic regions for 8 Jk(a-b-) samples were analyzed with PCR-sequence specific primers (PCR-SSP) and DNA sequencing. RESULTS: All samples had AA genotype at position 838 of exon 9 predicting a null Jk(b)-like alleles. Sequence analysis has revealed...
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