Article
Two novel SNPs of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene associated with growth and meat quality traits in the chicken.
Genetics and molecular research : GMR - 18 Sept 2012
Wei Y, Zhu S K, Zhang S, Han R L, Tian Y D, Sun G R, Kang X T
Abstract excerpt
The enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is rate-limiting for metabolism of cholesterol; it plays an important role in endogenous cholesterol biosynthesis. We used DNA sequencing technology and created restriction site PCR-RFLP to detect HMGCR SNPs in an F(2) resource po...
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