Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.

Scientific reports - 1 Jan 2012

Komarova Natalia L, Urwin Erin, Wodarz Dominik

Abstract excerpt

Complex traits can require the accumulation of multiple mutations that are individually deleterious. Their evolution requires a fitness valley to be crossed, which can take relatively long time spans. A new evolutionary mechanism is described that accelerates the emergence of complex phenotypes, based on a "division of labor" game and the occurrence of cheaters. If each intermediate mutation leads to a product...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Computer Simulation
Share to Genetic Fitness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Multifactorial Inheritance

Share to Mutation

Share to Phenotype

Share to Reproduction, Asexual

Source

Open in PubMed Open full text

Identifiers

PMID: 23209877
DOI: 10.1038/srep00917
PMCID: PMC3512085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.PMID 23209877Read ↗

Spatial interactions and cooperation can change the speed of evolution of complex phenotypes.Semantic proximity Read ↗

Genetic architecture promotes the evolution and maintenance of cooperation.Semantic proximity Read ↗

Complex role of space in the crossing of fitness valleys by asexual populations.Semantic proximity Read ↗

High relatedness maintains multicellular cooperation in a social amoeba by controlling cheater mutants.Semantic proximity Read ↗

Second-order cooperation: Cooperative offspring as a living public good arising from second-order selection on non-cooperative individuals.Semantic proximity Read ↗

Life cycles, fitness decoupling and the evolution of multicellularity.Semantic proximity Read ↗

A generalization of Hamilton's rule for the evolution of microbial cooperation.Semantic proximity Read ↗

With a little help from my friends: cooperation can accelerate the rate of adaptive valley crossing.Semantic proximity Read ↗

Division of labour and the evolution of multicellularity.Semantic proximity Read ↗

Cooperating mutations: joint forces, novel vulnerabilities.Semantic proximity Read ↗

Origins of multicellular evolvability in snowflake yeast.Semantic proximity Read ↗

The rate at which asexual populations cross fitness valleys.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.