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Article

[Clinical genetics of amyotrophic lateral sclerosis in Japan: an update].

Rinsho shinkeigaku = Clinical neurology - 1 Jan 2012

Aoki Masashi, Warita Hitoshi, Suzuki Naoki, Kato Masaaki

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disorder characterized by the death of upper and lower motor neurons. In familial ALS kinders with mutations in the SOD1 gene, the age of onset of weakness varies greatly but the duration of illness appears to be characteristic to each mutation. Mutations in the fused in sarcoma/translated in liposarcoma (FUS/TLS) gene have been discovered to...

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Source

Identifiers

PMID: 23196439
DOI: 10.5692/clinicalneurol.52.844

Genes

FUS
SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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