Article
Reproducibility of linear array for human papillomavirus genotyping.
Journal of clinical microbiology - 1 Feb 2013
Koshiol Jill, Dunn S Terence, Walker Joan L, Zuna Rosemary E, Schiffman Mark, Sherman Mark E, Gold Michael A, Allen Richard A, Zhang Roy, Wang Sophia S, Wentzensen Nicolas
Abstract excerpt
We conducted a Linear Array test/retest analysis using cytologic specimens from 198 women. A total of 67.2% of samples had the same human papillomavirus (HPV) types detected in both tests (type-specific positive agreement was 83.3% overall [Kappa = 0.9] and 86.8% for carcinogenic types [Kappa = 0.92]). Discordance was highest with a low hybridization signal strength. Overall, Linear Array was highly reproducible.
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