Genetic association of interleukin-1β (-511C/T) and its receptor antagonist (86-bpVNTR) gene polymorphism with susceptibility to bacteremia in kidney transplant recipients.

Abstract excerpt

BACKGROUND: Bacteremia remains a significant cause of morbidity and mortality after kidney transplantation. The present study was conducted to determine the influence of the polymorphisms of interleukin-1 β (IL-1 β) and IL-1 receptor antagonist gene (IL-1RN) on the susceptibility to bacteremia within the first year after kidney transplantation. METHODS: Twenty-one bacteremic and 60 noninfected kidney transplant...

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