Article
Persistent Enterovirus Infection in Culture-Negative Meningoencephalitis: Demonstration by Enzymatic RNA Amplification
1 Apr 1990
Abstract excerpt
Chronic meningoencephalitis due to enterovirus infection can occur in patients with antibody deficiencies. A modified polymerase chain reaction technique demonstrated persistent echovirus 11 infection in such a patient, despite negative routine viral cultures and negative routine nucleic acid hybridization. Although the sequence of echovirus 11 has not yet been determined, genomic conservation among the...
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