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Article

Overweight modulates APOE and APOA5 alleles on the risk of severe hypertriglyceridemia.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2013

Lee Ming-Jen, Chien Kuo-Liong, Chen Ming-Fong, Stephenson Dennis A, Su Ta-Chen

Abstract excerpt

BACKGROUND: This study aimed to investigate whether the body mass index (BMI) in combination with genetic variations in APOE and APOA5_'T' alleles modulates the risk of sHTG. METHODS: There were 255 moderate HTG (TG ≥2.26 and <5.65 mmol/L) and 176 sHTG (TG ≥5.65 mmol/L) and 304 controls (TG <2.26 mmol/L) were recruited. APOE epsilon alleles were genotyped using sequence-specific primers; the APOA5_'T' allele...

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Source

Identifiers

PMID: 23178747
DOI: 10.1016/j.cca.2012.10.054

Genes

APOE
APOA5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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