Article
Molecular platforms utilized to detect BRAF V600E mutation in melanoma.
Seminars in cutaneous medicine and surgery - 1 Dec 2012
Curry Jonathan L, Torres-Cabala Carlos A, Tetzlaff Michael T, Bowman Christopher, Prieto Victor G
Abstract excerpt
Metastatic melanoma (MM) is a deadly skin disease refractory to standard chemotherapy. Despite numerous clinical and pathological parameters derived to guide patient management, clinical outcomes in melanoma patients remain difficult to predict. There is a critical need to delineate the important biomarkers typical of this disease. These biomarkers will ideally illuminate those key biochemical pathways...
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